Associate Scientist, Cell Banking

Compass Therapeutics
Cambridge, MA

Compass Therapeutics is a fully-integrated drug discovery and development company focused on manipulating the immune system to treat human disease using our proprietary Targeted Immunomodulation™ platform. Compass is initially focused on developing cures for cancer by comprehensively drugging the entire tumor-immune synapse with combination therapies. Novel scientific insights are validated and explored deeply inside our labs before Compass pursues the best proprietary combinations of therapeutics into human clinical trials.

Compass has attracted $170M in Series A financing to fund our ambitious plan to build a fully- integrated biopharmaceutical company from the ground up. Our investors are among the most sophisticated venture capitalists in the industry who exemplify our philosophy of building long term economic value through our therapeutic pipeline. They include OrbiMed Advisors, F-Prime Capital, Borealis Ventures, Thiel Capital, Cowen Private Investments, GV, and Alexandria Real Estate Ventures.

Our Translational Immunology & Immunopharmacology Group is seeking a hands-on Associate Scientist at our Cambridge, MA site.

Principal responsibilities:

• Isolation and cryopreservation of various human immune cell types from blood samples
• Perform QC for each lot of prepared cells, documenting viability, purity and functionality
• Execute differentiation & activation protocols as required to support downstream assays
• Propagation and banking of engineered cell lines
• Maintain a database of all banked samples
• Cure cancer.

Preferred Qualifications:

• Must be highly proficient with human PBMC preparation by Ficoll gradient centrifugation
• Must be skilled with magnetic bead isolation of specific immune cell subsets (T cells, NK cells, monocytes)
• Excellent tissue culture skills and experience culturing human primary immune cells
• Prior experience working in a cell banking environment is highly preferred
• Experience utilizing LIMS software for data entry and sample tracking
• Skill with flow cytometry and cytokine measurement is a major plus
• Proficiency with protocols for differentiation and/or activation of human primary immune cells is highly desired (e.g., T cell activation by CD3/CD28 or PMA ionomycin, monocyte differentiation into macrophages by M-CSF, NK cell activation by IL-2 or IL-15)
• Must be highly organized with excellent attention to detail

Basic Qualifications:

• B.S. + 1-3y experience

We believe that science is bigger than any one person. Our legacy is what we achieve together. To that end, Compass Therapeutics offers individually-tailored compensation packages which include competitive cash compensation, meaningful equity participation, comprehensive healthcare and adoption benefits, continuous career development, sabbatical programs, education reimbursement and many other benefits aligned with our philosophy of putting our team first. Our labs are located at 245 First Street, Cambridge, MA.

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